教授风采
    教授风采
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发布人:化学化工
发布时间:2020-10-05
浏览次数:50

 

郭英姝,女,博士,于青岛科技大学获博士学位,教授,博士生指导教师,教育部新世纪优秀人才,山东省优青,山东省高等学校“青创科技计划”创新团队负责人。作为项目负责人,主持国家自然科学基金2项,教育部新世纪优秀人才支持计划,山东省自然科学基金省属高校优秀青年人才联合基金,山东省大型科学仪器设备升级改造技术研究专项等科研项目。以通讯作者或第一作者发表发表SCI论文30余篇,其中影响因子5.0以上20余篇。授权国家发明专利4项。研究成果获山东省高等学校科学技术奖二等奖、山东省自然科学学术创新奖、山东高等学校优秀科研成果奖(自然科学类)二等奖。指导硕士研究生十余名。当选《Frontiers in Chemistry》杂志编委。

研究方向:肿瘤标志物检测技术、生命影像化学、生物化学分析、核酸载体的研制及诊疗一体化的研究。

讲授课程:主讲普通生物学、化学生物学、分子料理与化学美食等。

代表性研究成果:

(1) Yingshu Guo, Yujie Wang, Guangxu Yang, Jing-Juan Xu,* Hong-Yuan Chen, MicroRNA-Mediated signal amplification coupled with GNP/dendrimers on a mass-sensitive biosensor and its applications in intracellular microRNA quantification [J]. Biosensors and Bioelectronics, 2016, 85: 897902 (IF= 10.257, SCI一区)

(2) Ying-shu Guo, Xue-mei Li, Su-juan Ye, Shu-sheng Zhang*, Modern optical techniques provide a bright outlook for cell analysis [J]. Trends in Analytical Chemistry, 2013, 42: 168-185IF=9.801, SCI一区)

(3) Yingshu Guo, Shuang Li, Yujie Wang, Shusheng Zhang*, Diagnosis–therapy integrative systems based on magnetic RNA nanoflowers for co-drug delivery and targeted therapy [J]. Analytical Chemistry, 2017, 89: 2267?2274  (IF=6.785, SCI一区)

(4) Yingshu Guo, Yujie Wang, Shuang Li, Li Niu, Di Wei and Shusheng Zhang*, DNA-spheres decorated magnetic nanocomposite based on terminal transfer reaction for versatile target detection and cellular targeted drug delivery [J]. Chemical Communication, 2017, 53: 4826 - 4829(IF=5.996, SCI一区)

(5) Yingshu Guo, Jia liu, Guangxu Yang, Xiaofeng Sun, Hong-Yuan Chen, Jing-Juan Xu*, Multiple turnovers of DNAzyme for amplified detection of ATP and reduced thiol in cell homogenates [J]. Chemical Communications, 2015, 51: 862-865 IF=6.164, SCI一区)

(6) Yingshu Guo,* Xiaofeng Sun, Guangxu Yang, Jia Liu, Ultrasensitive detection of ATP based on ATP regeneration amplification and its application in cell homogenate and human serum [J]. Chemical Communications, 2014, 50: 7659-7662IF=5.996, SCI一区)

(7) Meiju Niu, Yujie Wang, Shuang Li, Yingshu Guo*, Electrochemiluminescence detection of cancer cell based on an electrode surface-related “one-pot” cascade DNA auto-machine [J]. Sensors and Actuators B: Chemical, 2016, 223: 359364 (IF= 7.1, SCI一区)

(8) Yingshu Guo *, Shuang Li, Jia Liu, Guangxu Yang, Zhaomei Sun, Jun Wan, Double functional aptamer switch probes based on gold nanorods for intracellular ATP detection and targeted drugs transportation [J]. Sensors and Actuators B: Chemical, 2016, 235: 655662 (IF= 7.1, SCI一区)

   (9) Yingshu Guo,* Xiaofeng Sun, Youjian Fu, Yaning Mao, Isothermal amplified detection of reduced thiol through graphene oxide nanoscaffold and disulfide-bonded DNA tweezers [J]. Sensors and Actuators B: Chemical, 2014, 193: 107-112 (IF= 7.1, SCI一区)

(10) Yujie Wang, Xinxin Shang, Jia Liu, Yingshu Guo,* ATP mediated rolling circle amplification and opening DNA-gate for drug delivery to cell [J]. Talanta, 2018, 176: 652658 (IF=5.339, SCI一区)

联系方式:yingshug@126.com